Yes, it does work. In fact I am typing on it right now. I was undecided whether 8 or 16 GB of ram would be reasonable as an upgrade so, also out of curiosity, I went for 16 GB. The limiting factor, in my view, is the processor (and graphics chip) that are the first components to slow down the system and increase the fan speed. Other than that, for example for office applications, the MBP is still of great use. I am actually repeatedly stunned that this device is already 11 years old. We have installed an SSD several years ago and in my view, even before upgrading the RAM, this is the most important part to improve the system.
I have bought Mushkin components but this was due to availability reasons, I have installed OWC memory in my iMac and it runs flawlessly as well.
The 15" and 17" MBPs use a newer chipset with integrated graphics. These graphic components seem to be limiting the memory size to 8 GB, the 13" is still using a Core 2 Duo with separate graphic chipset and therefore is able to address all 16 GB.