iPhoto isn't seeing the iPhone and neither is Image Capture. When I boot up Image Capture, it says "No camera or scanner connected."
I would be checking your cord you are using to connect to your Machine, as well as trying the USB with another device to make sure the USB is working.
From here, its just a matter of fault finding now and see what we come up with.
Do you open the Apps then connect your phone, or do you have you phone connected then open the Apps ?? Does it show up in iTunes ?? If it does, and now i know you have iPhoto, why not use iTunes to do all your syncing as Chas_m mentioned in post #2 ??
Do you have iCloud set up as well ?? If so then you should get the Photo Stream magically appear with all the pictures in iPhoto when you open it up. Then you dent need to Sync or upload/download your images..
Tell us what you have set up, What iOS is on your iP4s, what OS you have on your Mac as well. We need as much info to help you out, and it would be good for you to put them under your Avatar ….
More info, More help