Type the name of the file - File pops up
TAB - begin typing Open With - the Command Open With is active
TAB - Begin typing NeoOffice - NeoOffice is selected
Each tab action brings me to another part of the 'sentence.'
NeoOffice launches the file and you're done. You can do the same with a file and Mail. You can have Quicksilver attach the file to a new message. You can have Quicksilver play a song in iTunes. You can have Quicksilver open a contact from your address book and email them.
That sounds like a load of work to me! LOL