While it is true, you can simply delete the programs you no longer use, and probably would gain nothing from a 'fresh start', I don't like the idea of trialware spitting files throughout my system without my permission/knowledge.
Its just too.. Windows.
For example, if you install a trial program, and later delete it, and again install the same program, you will find that not only does it remember your trial has expired, but it often remembers your user preferences! Even using the popular 'AppZapper' doesn't get rid of all the files.
Sure, the files are miniscule in size, and not affecting performance, but I don't want them for all eternity.
-Sab