Call me a Zen Buddhist, but that screen seems WAY WAY too busy in every respect.
Unlike a LOT of people here, I'm not a fan of Geektool and the stuff it puts up all the time all over the screen. So I'd start by disabling that. All those functions are easily duplicated by widgets, which only slide into view when you want them. Much better IMO.
Next, the menubar. Do you really *need* to monitor your machine that closely *all the time?* This seems like Stinkin' Windows Thinkin' to me and again I'm not a fan. I'd dump the iStat Menus and just (again) just the iStat widget for those occasions where I actually need that information.
I see from your screenshot that you also have Norton Virus installed. (yes, Norton is ITSELF a virus IMHO, not an anti-virus). Please uninstall that (properly) immediately, it's not only not doing you any good, it does HARM.
Third, folders on the desktop always look ugly, because they obscure a beautiful desktop. Move those folders to their proper place (Pictures for the bottom two, Documents for the first one and that last RTF file).
Finally, your Dock is way overcrowded. You could consolidate some thing there. For example, instead of three icons for iWork, just drag the iWork folder to the dock (right side) and make it a stack. Voila! One icon does the work of three. You could do the same for iLife (though you have to make your own folder for that), pull the Dashboard icon off (it's usually invoked by keyboard command anyway), and just generally trim off any less-used icons and instead use the Application folder icon in the dock (as I see you ahave already done) to get to those less-used apps.
That should make your desktop a much more beautiful and serene environment in which to work.