Hi Sue,
worn contact lenses for decades - now I use bifocal contact lenses - Feel 15 years younger!
That puts you in the paediatric group - not sure the Mac-Forums allow children to post!;P BTW, my wife has worn
hard contact lenses for 47 years, which is not far off some kind of record.
From a logical perspective, the higher the resolution, the clearer the image, and the more it can be magnified or enlarged without distortion. Theoretically, this should produce less eye strain if the font size and corresponding data are optimised by the user.
I feel that eye strain has the following major components: the number of hours at the screen in total/day; the length of each session before a 5-10 minute break; the brightness of the screen.
To minimise these, force yourself to have at least 5-10 minutes break after each hour on screen; adjust the brightness down to comfort levels during the day; use an app like f.lux to adjudt the colour hues appropriately for evening and nightime work.
Ian