I have a apache2/php5/mysql5 setup on tiger. The wordpress site runs fine to start with, but after a while (usually a couple of hours) the site slows down upon every request. When the slowdown occurs there is also a lot of disk activity, like something is being cached on disk. The Mac Pro has 8GB Ram installed so its not a shortage of resources. When I restart the mysql service the problem goes away for a few hours the repeats. I have sripted a service restart cron job every hour to get around this but if anyone has come across this before can the sing out!!