Hi Designer,
I've Got a 3Ghz Quad-Core, 4Gb Ram and the QuadroFx4500.
I can't compare this Graphics Card to the ATi as i haven't used one in the MacPro, but from what i've read and what My Card does, is that if you want a Gaming Card go for the ATi, but if your into Graphics Intensive Work (AfterEffects, Cinema4D, Photoshop etc) and Have The Money go for the QuadroFX, when i use AfterEffects with some fairly big compositions, the Graphics card Does alot of the Work, i can't wait to pump more ram into it.
Again though, If your a gamer don't get the Quadro, if your a Video Editor/VFX User then it's the Best Card Available for the MacPro To Date.