Accessing an external hard drive wirelessly

Hello, I've got a MacBook, and I recently purchased an Iomega 320GB external USB hard drive for it. I just wondered if there was any possible way to access the contents of the said hard drive wirelessly. I don't know if this is classed at networking, and if it is, I don't know the first thing about it. I'd really appreciate it if could let me know if it's possible, and if it is, in the simplest possible terms, what I'd need to do it and how exactly to set it up. Thanks in advance, and excuse my ignorance.
-Tom

The hard drive would need to be connected to some computer on your network for you to mount it wirelessly.