Basically you fire up the program, select a disk to be copied in the left drop down menu, select a copy location in the right drop down menu.
Hit copy and Superduper will erase the destination drive, copy everything over and make the new drive bootable.
Easy as pie!
To boot off your backup, either go to system preferences->startup disk and select it there, or hold down option at startup and select it then.
If you want more advanced options you'll need to purchase a license for Superduper.