Haven't had a chance to look the new iTunes over vert thoroughly, but something sorta funny/strange happened when I updated it on my new iMac (haven't had a chance to investigate this on my MBP yet).
The wife and I both have an iPhone 5 and we have one iPad in the house. The settings for syncing are the same for all 3 devices - wireless sync whenever iTunes is opened, but don't automatically open iTunes when a device is detected. Somehow that last setting for the iPad only was changed and the box was checked to open iTunes whenever that device is detected. I noticed the last 2 times I used the iMac this weekend that iTunes was open. I'm pretty meticulous about ejecting my iOS devices and quitting iTunes before putting the iMac to sleep. I rarely have iTunes open for anything anyways, other than to sync once a week. So I thought my wife opened it and left it open. She said she hadn't even been on the iMac for over a week. So it had to be the update that made that one preference change. Not harmful, not a big deal, just odd.
Thought I'd share that....