MacBook OS Crash? Circle with Slash

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Was watching netflix and suddenly the computer froze. I tried restarting and immediately got the circle with slash in place of the apple logo. I started it up in Safe Mode and got the following errors. "Read Error 0x7" and "Error loading kernel 'mach_kernel' (0x12)"

Any advice would be greatly appreciated.
 
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Sorry - it wasn't safe mode is was Command + S (whatever that is). I tried to boot in safe mode (holding shift). The apple and spinning gear appears for a while then a blue screen with the mouse cursor appears. Then the screen switching between different shades of blue/grey with the spinning gear on the bottom for a while and nothing else happens but this over and over. I've been staring at it for 10+ minutes.
 

chscag

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Your Mac's Specs
2017 27" iMac, 10.5" iPad Pro, iPhone 8, iPhone 11, iPhone 12 Mini, Numerous iPods, Monterey
What happens when you boot the machine with your original install DVD and run Disk Utility, Verify and Repair from the disk?
 

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