90% of CPU used by Flash Player (Safari Internet Plug-in)

As seen in the attached picture, obscene amounts of my memory is used by this one... thing. I don't know what it is, but it's causing my fan to sound like a 747. Is there any way to get rid of this? Help!

Yes - quit whatever's using flash. Safari can get locked up sometimes - quit Safari and restart and I bet it goes away. Use an extension like click-to-flash so you can pick and choose what flash is running.

Yikes, what kind of Mac is this? Macbook? iMac? Specs?

This is one of the reasons everyone wants Flash to be placed in the scrap heap. I second Brian's advice about Click-To-Flash if you must use it. Alternately, why not try uninstalling it for a while? More and more sites are going away from it.