I will miss the iWeb/
MobileMe/iDisk integration as well, but won't miss spending $100 a year for it.
I think (my opinion) that this is Apple's "gentle" way of encouraging -- without specifically endorsing -- alternative options that are actually more powerful and in some ways easier to accomplish the kind of things people want to do with websites nowadays. I think Apple support got tired of questions like "how do I set up a storefront on my iWeb site" and "how can I edit an iWeb site on a different Mac or a PC?" etc.
The truth of the matter is that iWeb really needed a complete overhaul, not least of which in order to make its generated code cleaner and more editable outside iWeb. Apple has chosen not to devote the resources to do this, in part because programs like Rapidweaver (et al) do it a lot better.
As for uploading, WebDAV and built-in FTP in some web-building programs make the process pretty much just as easy as MM publishing.
Finally, iDisk isn't really going away -- it's shrunk down to 5GB in "available" space, but has actually grown in size since photo-streams and certain other things don't count against that space. For those who use the iDisk primarily to host photo and video galleries, Flickr Pro ($25/year) is actually a fantastic deal (while not quite as stylish, I'll admit).
For people like me who hosted podcasts on our iWeb-generated, MM-hosted websites, it's a little bit more of a change -- but frankly I'd been itching to move to Wordpress anyway, and so really the only thing I have to do that I wasn't going to do anyway is find new hosting for the podcast files and adjust the RSS feed. A little bit of a PITA, yes, but not really that big a deal if one accepts the concept that things change every few years no matter what you do.
