Use the apps that Apple have already made for it! Notes app on iPhone syncs with Mail app on Mac OS X. Hope this helps?
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Free app. Syncs your handheld notes instantly with your desktop app via WiFi & 3G. Works great. I use it to keep my life organized.
Hey, i just read through the reviews on the App store, a few really bad points, for some reason it requires an internet connection to use it, and the updates can be buggy