Thing is, these examples can be said about any round size. I've read about a person taking a 45acp to the chest and walking away in NYC. FMJ vs JHP is the real defining comparison if you really want to cause damage with less shots. I bought a Ruger LCP 380 after an awkward moment where carrying anything larger would make me stand out in a crowd I did not want to stand out in. Been testing it out for a bit now, and if you can't make that bullet useful, you shouldn't be shooting. As ammo goes, each has it's cons in relation to amount of material you are seeking to go through before lethal penetration. The 380 round, as most rounds, are designed to penetrate ~12 inches under normal clothing. With so many 380 variations, you have choices between penetration, spread, and both. If you are worried about penetration, you have the option of Remington Gold Saber. Generally, those 380's that inflict the most internal damage are those with the lowest penetrating power(9"), but if you're after only penetration(which is not really what you want in defense) 14" of penetration is also found in some 9mm, .40, and 45acp rounds. Test also show that .380 vs 9mm performance equals out with smaller handguns. Pick what you prefer.
I use these three, in this order as pictured: .380, 9mm, and 45acp.
Use .380 Federal Champion 95gr, 9mm Hornady Critical Defense 115gr FTX, and .45ACP Hornady Custom 185gr XTP for my defense loads. Each has its own purpose. No bad guy will have a good time at my house.
Not sure if I posted this before:
Awesome pocket handgun.