MacBook - Touchpad not responding to clicks, 3rd party usb mouse not working either

Hi everyone, I have a unibody aluminum macbook which I purchased at the end of November 2008. During the last few months the touchpad periodically stopped responding to clicks of the touchpad and now it has stopped responding all together. Tap-to-click feature does work however. Using a USB mouse works sporadically at best and during the last week that stopped working all together as well, and the mouse works on other computers. I'm sorry if this has been posted before but can someone help me out and what to do about this. Thanks so much!