400 is best for storage drives and yes theres a difference. How large it is depends on how you use your MB. The thing to make your MB fly is a SSD drive though. That is like night and day. You could consider a say 120 or 240 gb ssd and then swap" /> Mac Forums - View Single Post - cheapest place to buy an internal hard drive?(uk)
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monosan

 
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5400 is best for storage drives and yes theres a difference. How large it is depends on how you use your MB. The thing to make your MB fly is a SSD drive though. That is like night and day.
You could consider a say 120 or 240 gb ssd and then swap the dvddrive with an extra data/storage drive
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