There are hundreds of stations on iTunes Radio
Some are heavily processed, and some are pretty clean. There is a great variety of music available, so you are bound to find something you like.
Personally I have loaded all my CDs, my downloads, and a few borrowed from the public library into iTunes. A little over 4,000 songs. Playback is not as clean as CDs, but I can't take a CD, create a bunch of Smart Playlists, and put it on shuffle. That's what I like to do.