Interesting, Mike. Thanks for the link. This is one feature I really miss since I've moved up to CS5 on my MBP.
I have an old Canon Canoscan 4400F set up to attach (when needed) to my MBP, and I've worked around this by just using the CanoScan Toolbox. Before I installed the scanner on my computer, though, I made sure to download and install the latest driver and software straight from the Canon website, which has worked well. I set up the toolbox to open scanned images straight into PS, so not having the TWAIN capability hasn't really been an issue.
Perhaps this will work with an Epson, too? The only reason I suggest this is because the Adobe website does mention that this plug in may cause crashes, which I have experienced with PS every once in a while with this machine. The crashes don't seem to occur (according to the multiple posts on the Adobe boards) in Lion, but they do in Snow Leopard (which I have).
Just a thought for others like me who work with scanners and PS.