I have just set this up on my home network. Have only one 750GB LaCie desktop USB drive connected via powered hub, and have also connected another desktop FAT32 drive same way. LaCie is partitioned, half in HFS+ for time machine backups for two Mac laptops, the other half in FAT32 for general storage and iTunes library (all files in Apple lossless format).
But have two problems with the AP extreme when trying the following:
1. Laptop connected by wireless to the AP extreme, listening to my iTunes library on the laptop. Occasional periods of silence where music cuts out. Seems to be either the wireless signal being interrupted, or HD data transfer. Annoying, and should be corrected when I get my Sonos and connect by ethernet cable. I have to think that if the AP extreme is good for HD video streaming it could also stream my music in lossless format without interruption.
2. Related to #1, doing what I describe in #1 while loading CD's into my iTunes library, data is transferred by wireless, not hardwired to router. It works for a short time, then the drive gets disconnected. I can only reestablish the connection to the drive by shutting down the computer and rebooting, even need to reboot the AP extreme as it will recognize the drive (after laptop reboot) but can not mount it.
Router is located on first floor of my small house, near a TV with wireless Roku but these are OFF when this happens, and no other data-intensive activity is taking place on the network. At worst the other mac laptop is web surfing. AP extreme is configured using the default apple settings.
Comments appreciated.